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While the exact mechanisms have not yet been elucidated, age-related aberrations in endometrial stromal cell decidualization may play a fundamental role

Upcoming patent expirations could pave the way for more affordable generic options in the future

Interventional studies have shown that pharmacological agents targeting metabolic and hemodynamic stress, such as SGLT2 inhibitors, GLP-1 receptor agonists, and renin-angiotensin system blockers, can partially restore plasma and urinary acylcarnitine levels

ROS can modify sperm proteins, leading to structural changes that impair motility, metabolic processes, and the sperms ability to bind to the oocyte